摘要
目的:观察新生儿无乳链球菌败血症的临床耐药情况。方法:选择无乳链球菌败血症患儿45例,记录每例患儿基本资料及无乳链球菌的临床药敏情况。结果:无乳链球菌败血症患儿的菌株对7种抗菌药物的耐药率从高到低依次为克林霉素73.33(33/45)、红霉素64.44%(29/45)、左氧氟沙星42.22%(19/45)、利奈唑胺2.22%(1/45)、青霉素、万古霉素、头孢曲松。结论:无乳链球菌败血症患儿对克林霉素、红霉素、左氧氟沙星和利奈唑胺等抗菌药物均有不同程度的耐药,而头孢曲松、万古霉素和青霉素尚未发现耐药性,故可作为治疗新生儿无乳链球菌败血症的临床首选药物。
Objective： To study the clinical drug resistance of neonatal Streptococcus agalactiae sepsis. Methods： 45 children with Streptococcus agalactiae sepsis were selected,and their basic data and clinical drug sensitivity of Streptococcus agalactiae were recorded. Results： The resistance rates of the children with Streptococcus agalactiae sepsis to 7 kinds of antimicrobial drugs were（ from high to low） were 73. 33%（ 33/45） of Clindamycin,64. 44%（ 29/45） of Erythromycin,42. 22%（ 19/45） of Levofloxacin,2. 22%（ 1/45） of Linezolid,Penicillin,Vancomycin,and Ceftriaxone. Conclusions： The children with Streptococcus agalactiae sepsis have a certain resistance to Clindamycin,Erythromycin,Levofloxacin and Linezolid; however,the resistances to Ceftriaxone,Vancomycin and Penicillin are still unknown. Therefore,they can be used as a therapeutic drug of choice.
出处
《中国民康医学》
2017年第4期27-28,共2页
Medical Journal of Chinese People’s Health
关键词
新生儿
无乳链球菌
抗菌治疗
耐药性
Newborn
Streptococcus agalactiae
Antibiotic therapy
Drug resistance
作者简介
赵侗玲（1979.7-）,籍贯：辽宁省,大学本科,研究方向：临床检验和微生物检验.
