摘要
尿酸是人体内嘌呤代谢的一种终产物,尿酸水平的升高与动脉粥样硬化的形成密切相关,血尿酸可以通过一系列机制促进动脉粥样硬化的形成。颈动脉粥样硬化是评估全身动脉粥样硬化的一个窗口,颈动脉内中膜厚度(CIMT)则是反映颈动脉硬化程度敏感性和特异性较高的指标之一,也是评价动脉粥样硬化损害的重要指标,近年来被广泛运用于临床检查。高尿酸血症可以增加心脑血管疾病的风险目前已得到临床证实,了解高尿酸血症与颈动脉粥样硬化的相关性对于预防及治疗心脑血管疾病具有重要意义。
Uric acid(UA) is the end product of purine metabolism, UA level is closely related with the formation of atherosclerosis, atherosclerosis may be formed by a series of mechanism of blood UA. Carotid atherosclerosis is a evaluating window of systemic atherosclerosis, carotid artery intima-media thickness(CIMT) is one of the indexes to reflect the degree of carotid artery atherosclerosis with high sensitivity and specificity, and is also an important indicator to evaluate atherosclerotic lesions, in recent years, is widely used in clinical examination. It has been proved that hyperuricemia can increase the risk of cardiovascular and cerebrovascular diseases in clinic, to understand the relationship between hyperuricemia and carotid atherosclerosis has important significance for prevention and treatment of cardiovascular and cerebrovascular diseases.
出处
《中华临床医师杂志（电子版）》
CAS
2015年第23期140-142,共3页
Chinese Journal of Clinicians(Electronic Edition)
作者简介
刘彬,Email：18674602345@163.com
