摘要
目的分析透析依赖的终末期肾病患者合并严重冠心病行冠状动脉旁路术的临床资料,总结围术期规律,提出治疗方法。方法回顾性分析2006年1月1日至2013年8月20日北京安贞医院透析依赖患者的单纯冠状动脉旁路移植术共40例的临床资料,其中男27例、女13例,平均年龄(63.52±9.17)岁。33例采用非体外循环冠状动脉旁路移植术,为非体外循环组;7例采用体外循环冠状动脉旁路移植术,为体外循环组。结果平均搭桥数(2.72±0.68)支。住院期间,非体外循环组1例死于围术期心肌梗死,死亡率3.0%。体外循环组死亡2例,死亡率28.6%:1例术后15 d死于严重感染,继发多器官功能衰竭;1例术后第4 d死于心室颤动。术后随访率100.00%,随访时间平均(4.3±2.1)年。全部患者术后1年、3年、5年生存率分别为92.68%,89.43%,82.04%。结论透析依赖的终末期肾病患者因合并严重冠心病可行冠状动脉旁路移植术,但手术死亡率较高。严格掌握手术适应证,合理选择手术方式及正确的围术期处理,尤其连续性肾脏替代治疗(CRRT)的积极应用可以使此类患者获得较好的治疗效果。
Objective To explore the safety and efficacy of patients with dialysis-dependent end-stage renal disease who underwent coronary artery bypass grafting（CABG）. Methods We retrospectively analyzed the data of 40 dialysis-dependent patients who underwent CABG in Beijing Anzhen Hospital between January 1, 2006 and August 20,2013. There were 27 male and 13 female patients at mean age of 63.52±9.17 years. Of them, 33 patients underwent off-pump CABG were in the off-pump CABG group, while 7 patients underwent on-pump CABG were in the on-pump CABG group.Results The average number of the grafts is 2.27±0.68. In the off-pump CABG group,1 patient died from perioperative myocardial infarction with mortality of 3.0%.In the on-pump CABG group, the operative mortality was 28.6%, with 1 death because of serious infection and secondary multi-organ failure 15 days after the operation, and another death because of ventricular fibrillation 4 days after the operation. The follow-up rate was 100.00%. Overall mean follow-up time was 4.3±2.1 years. During the follow-up, the overall survival rate at 1 year, 3 years, and 5 years was 92.68%,89.43%,and 82.04% respectively. Conclusion CABG can be performed in the patients with dialysis-dependent end-stage renal disease who also suffered with severe coronary artery disease, despite higher mortality. Surgeons should carefully select patients for the operation. Through optimal way of revascularization, and reasonable perioperative therapy, especially more actively use of continues renal replacement therapy, good results could be got in those kinds of patients.
出处
《中国胸心血管外科临床杂志》
CAS
CSCD
2015年第5期442-445,共4页
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
关键词
透析依赖
终末期肾病
冠状动脉旁路移植术
Dialysis-dependent
End-stage renal disease
Coronary artery bypass grafting
作者简介
通讯作者：迟立群．Email：chiliqun2002@qq．com
