摘要
目的：研究玻璃体切割术后早期及晚期眼压升高的发病率及病因。方法回顾分析235例（306眼）于我院行玻璃体切割术患者的临床资料，应用非接触式眼压计测量患者术前、术后早期（术后2周内）和术后晚期（术后6个月及以上）眼压，并分别对引起术后早期及术后晚期眼压升高的危险因素进行统计分析。结果306眼术前眼压平均值为（15.3±4.1）mmHg，随访时间6~20个月（平均14.3个月）。术后早期有42眼（13.7%）发生高眼压[平均值（31.9±6.0）mmHg]。术后晚期有12眼（3.9%）发生高眼压[平均值（32.1±5.7）mmHg]。Logistic回归分析结果显示：晶状体切除、巩膜环扎、睫状体光凝、惰性气体填充、硅油填充及糖尿病视网膜病变是术后早期发生高眼压的独立危险因素；晶状体切除、巩膜环扎、全视网膜光凝、硅油填充、糖尿病视网膜病变及颈动脉狭窄是术后晚期发生高眼压的独立危险因素，而光凝方式中睫状体光凝是术后晚期发生高眼压的保护因素。结论引起玻璃体切割术后发生高眼压与眼内填充物的不同、联合手术的方式、病种及颈动脉狭窄等有关。术后晚期眼压升高危害较大，术后晚期是否发生高眼压与早期高眼压无关。
Objective To research the incidence and etiological factors of intraocular pressure（IOP）elevation in patients in early and late postop-erative stages after vitrectomy. Methods The clinical data of 235 cases（306 eyes）who underwent vitrectomy in our hospital were respectively ana-lyzed. IOP was measured before operation,in the early postoperative stage（within 2 weeks）and in the late postoperative stage（6 months after opera-tion or longer）by non-contact tonometer. Risk factors related with ocular hypertension happened in the early and late postoperative stages were statis-tically analyzed. Results The mean average IOP before operation was 15.3 ± 4.1 mmHg for the 306 eyes. Within the follow-up period of 6-20 months（mean,14.3 months）,ocular hypertension occurred in 42 eyes[incidence,13.7%;mean,31.9 ± 6.0 mmHg]in the early postoperative stage and in 12 eyes[incidence,3.9%;mean,32.1 ± 5.7 mmHg]in the late postoperative stage. Logistic regression analysis revealed that lensecto-my,scleral buckling,cyclophotocoagulation,inert gas filling,silicone oil tamponade and diabetic retinopathy were the independent risk factors of oc-ular hypertension in early postoperative stage after vitrectomy,while lensectomy,scleral buckling,pan retinal photocoagulation,silicone oil tampon-ade,diabetic retinopathy and carotid artery stenosis were the independent risk factors of ocular hypertension in late postoperative stage after vitrecto-my. In addition,cyclophotocoagulation was a protective factor of IOP in the late postoperative stage. Conclusion The risk factors of ocular hyperten-sion after vitrectomy include the intraocular gapfiller,the mode of combined operation,disease type and carotid artery stenosis. IOP elevation that happens in the late postoperative stage is more harmful. Ocular hypertension in the late postoperative stage is not associated with that in the early stage.
出处
《中国医科大学学报》
CAS
CSCD
北大核心
2015年第5期429-433,共5页
Journal of China Medical University
作者简介
韩婧楠（1987-），女，医师，本科．
通信作者：才娜，E-mail：caina0413@aliyun．com
