摘要
目的:探讨肾孤立性纤维性肿瘤的影像学特征、病理学特征。方法:对1例直径1cm肾孤立性纤维性肿瘤患者术前进行彩色超声、CT及MRI检查,术后进行病理学观察及免疫组化标记,并结合相关文献进行分析。结果:影像学检查提示为肾实质性肿瘤。术后病理检查显示梭形肿瘤细胞排列无明显特征,但含有较丰富的薄壁血管和灶性胶原纤维束;瘤细胞表现温和,界限不清晰,胞质红染,核仁不明显,核分裂象少见,免疫组织化学检查:CD34、vimentin、bcl-2、CD99、CD10均阳性,CD31、SMA、desmin、S-100、PCK、EMA、CD21、CD23均阴性,Ki-67增殖指数为5%。结论:原发性肾孤立性纤维性肿瘤临床十分罕见,小肿瘤的影像学表现可能有某些特征,但仍需要病理学检查确诊。
Objective： To explore the histopathologic and imageological features of solitary fibrous tumor （SFT） of the kidney. Method：One case of SFT of the kidney with 1 cm in diameter was detected by ultrasound, abdominal CT and MRI preoperatively. Postoperative pathological examination was also taken. Then relevant lit- eratures were reviewed as a referrence to the data of the patient. Result： Imageological examinations showed renal parenchymatous tumor. On pathologic examination, spindle tumor ceils were arranged in no particular pattern, with numerous thin-walled vessels and collagen fiber bundle. It also showed that tumor cells were mild with ob- scure boundary, eosinophilic cytoplasm, inconspicuous nucleoli and rare mitosis. Immunohistochemical staining showed that CD34＋, vimentin＋, bcl-2＋, CD99＋, CD10＋, CD31--, SMA--, desmin--, S-100--, PCK--, EMA--, CD21--, CD23--. Proliferation index of Ki-67 was 5 %. Conclusion： Primary solitary fibrous tumor of the kidney is very rare. Some characteristics of such small tumors may be seen through imageological examinations, but the final diagnosis still depends on pathological examinations.
出处
《临床泌尿外科杂志》
2013年第12期929-931,934,共4页
Journal of Clinical Urology
关键词
肾肿瘤
孤立性纤维性肿瘤
影像学
病理学
kidney neoplasms
solitary fibrous tumor
imageology
pathology
作者简介
通信作者：刘继红，E-mail：jhliu@tjh．tjmu．edu．cn
