摘要
目的:评价针刺围刺、艾灸、中药热敷治疗局限型硬皮病的临床疗效及安全性。方法:将42例局限型硬皮病患者随机分为针药组(23例)、肝素钠组(19例)。两组均口服积雪苷片及维生素E,在此基础上,针药组加用围刺局部、艾灸局部及合谷、足三里穴,配合"热敷药"外敷局部;肝素钠组加用肝素钠软膏外用。两组均连续治疗6个月,比较两组治疗前后皮肤硬化积分、关节痛积分、关节功能积分,对中医证候疗效及安全性进行评估。结果:针药组治疗后患者皮肤硬度积分、关节痛积分、关节功能积分均较治疗前显著降低(均P<0.01),肝素钠组皮肤硬度积分较前改善(P<0.05),且针药组3项积分均显著低于肝素钠组(均P<0.05);针药组总有效率为86.4%(19/22),明显优于肝素钠组的52.6%(10/19,P<0.05)。结论:围刺、艾灸及中药"热敷药"外敷可改善局限型硬皮病患者皮肤硬化,疗效显著且相对安全。
Objective To assess the cIinical efficacy and safety of surrounding needle, moxibustion and hot compress of TCM herbs for localized scleroderma. Methods Forty-two cases of localized scleroderma were randomly divided into an acupuncture ＋ herb group （23 cases, group A） and a heparin sodium group （19 cases, group B）. Both the two groups were orally administrated with centella triterpenes tablets and vitamin E, group A was additionally treated with surrounding needle at local area, moxibustion at affected site and Hegu （LI 4）, Zusanli （ST 36） as well as hot external application of ＂hot compress herbs＂ at local location, while group B was treated with external application of heparin sodium cream. Both the two groups were treated for consecutive 6 months, and scores of skin sclerosis, joint pain and function were compared before and after the treatment. Also the efficacy and safety of TCM syndrome were assessed. Results Compared with that before the treatment, the scores of skin sclerosis, joint pain and joint function in the group A after treatment were significantly decreased （all P〈0.01）, the score of skin sclerosis in the group B was improved （P〈0.05）, and the three types of score in the group A was obviously lower than those in the group B （both P〈0.05）. The total effective rate was 86.4% （19/22） in the group A, which was superior to 52.6% （10/19） in the group B （P〈0.05）. Conclusion The surrounding needle, moxibustion and external application of ＂hot compress herbs＂ could improve skin sclerosis in patients with localized scleroderma, which has obvious efficacy and relative safety.
出处
《中国针灸》
CAS
CSCD
北大核心
2013年第5期403-406,共4页
Chinese Acupuncture & Moxibustion
基金
陕西省中医管理局中医药科研课题资助项目:lc34
陕西省科学技术研究发展计划资助项目:2009K01-82
关键词
硬皮病
皮肤硬化
围刺
热敷药
艾灸
scleroderma
skin sclerosis
surrounding needling therapy
hot compress herbs
moxibustion
作者简介
第一作者：闫小宁（1971-），男，副主任医师。研究方向：硬皮病的发病机制及临床治疗。Email：yanxiaon2005@126.com
