摘要
目的了解本地区女性人乳头瘤病毒(HPV)感染情况及高危因素,为该地区女性生殖器疣、宫颈癌防治及流行病学研究提供一定的依据。方法采用前瞻性研究方法,队列为本区普通女性2663例,用PCR、HCⅡ技术检测HPV感染及亚型分型情况。结果检测2663例,HPV感染214例,感染率为8.03%。高危险型HPV198例,占HPV感染亚型总数的86.48%。其中以亚型HPV52最多,占29.69%,HPV16占20.09%,HPV58占13.1%。结论本地区普通女性HPV感染率为8.03%,大多数是高危险型,HPV亚型前3位为52、16、58.这种HPV分型基因检测对于生殖器疣以及子宫颈癌的预防及治疗具有重要意义。
Objective To investigate the distribution of different human papillomavirus（HPV） subtypes infection of women cervixes in the region and the high risk factors of HPV infection,in order to offer evidences for the epidemiology of HPV and prevention of genital warts and cervical cancer in the region.Methods A prospective research method is adopted,the queue comprises 2663 female cases in the region,and PCR、HCⅡ technique is used to detect HPV infection and subtype classification situation.Results In 2663 cases,214 cases have HPV infection,the infection rate is 8.03%.198 cases have high-risk type HPV accounting for 86.48% of the total number of HPV subtype infection.Patients with subtype HPV52 are the most and account for 29.69%,HPV16 is 20.09%,and HPV58 is 13.1%.Conclusion The infection rate of women cervixes is 8.03% in the region.The most of subtypes are the high risk types.HPV 52 occupied the first of all subtypes,followed by HPV16 and HPV58.The distinction of HPV genotypes plays an important role in prevention and management of genital warts and cervical cancer.
出处
《当代医学》
2011年第21期20-21,109,共3页
Contemporary Medicine
关键词
女性生殖道
HPV感染
亚型
Female genital tract
HPV infection
Subtype
