摘要
通过以γ射线照射的K562细胞及自身PBMC作为饲养细胞进行NK细胞的克隆化培养,分别建立了IL-4和IL-2依赖的NK细胞克隆,并发现IL-4依赖的NK克隆代表未成熟的NK细胞。探讨了N细胞的分化发育过程及其调控因素。
After co-culture with nurses cells, for example, g-ray irradiated K562 cells or aulologous PBMC, the IL-2-dependent or IL-4-dependent NK cell clones have been established and found that the IL-4-dependent NK cell clones are immature or precursor NK cells. The differentiation and developing process and their controlling factors are also discussed in this paper.
出处
《中国科学基金》
CSCD
1999年第5期262-266,共5页
Bulletin of National Natural Science Foundation of China
