摘要
椎间盘退变疾病越来越被大家所重视,但退变的生物学机制尚不明确,构建椎间盘退变模型是研究的基础和关键。近年来国内外报道的新型椎间盘模型分为动物体外模型和动物体内模型两大类。动物体外模型包括椎间盘细胞模型和椎间盘组织块模型;动物体内模型有机械力学模型和外伤模型等。该文就近年来新型椎间盘退变模型的研究现状与进展作一综述。
The disc degeneration disease has been main research focus in spinal surgery, but the pathogenesis of disc degeneration is still not clear. Appropriate animal models are important for the study of pathogenesis of disc degeneration. Presently, models of disc degeneration are mainly classified into two categaries ： vitro models and vivo models. The animal vitro models include disc cell models and disc tissue models. The vivo models include mechanics models and trauma models. This review tries to give a short introduction about the status and progress of animal model about disc degeneration.
出处
《中国矫形外科杂志》
CAS
CSCD
北大核心
2009年第23期1804-1806,共3页
Orthopedic Journal of China
关键词
椎间盘退变
动物模型
进展
disc degeneration
animal model
congress
作者简介
吕明（1981-），男，山东枣庄人，医学硕士，研究方向：脊柱外科，（电话）010-88276622，（电子信箱）tvmingdoctor@163．com
通讯作者：（电话）13801233500，（电子信箱）pengbaogan@163．com
