摘要
对代谢组学的概念、基本原理、检测手段等做了简要介绍,综述了代谢组学技术在心血管疾病的病理生理学基础、早期诊断以及预防和治疗方面的现状。并对代谢组学在心血管疾病研究中的发展作出展望。
The concept, theory, and classiC of metabonomics are introduced. In data acquisition platform, NMR, MS, LC/MS are the prevalent techniques, ahhough at present, none of them is a perfect technique that could meet with the requirement of the metabonomics for measuring all metabolites. Recent advancements and applications of metabonomics in cardiovascular disease are reviewed. It can be expected that with the development of the data acquisition platform, metabonomics will play a major role in the disease diagnostic biomarkers and cardiovascular disease.
出处
《现代预防医学》
CAS
北大核心
2009年第6期1172-1173,1181,共3页
Modern Preventive Medicine
基金
国家高技术研究发展计划(863计划)(2006AA02Z4C8)
关键词
代谢组学
心血管疾病
核磁共振
病理学
Metabonomics
Cardiovascular disease
Nuclear magnetic resonance
Pathology
作者简介
王泳钦（1982-），女．硕士．研究方向：卫生毒理学
通讯作者：姚林，E-mail：yaolin766@sohu.com
