摘要
目的探讨听神经病患者人工耳蜗植入后的电生理结果变化并分析其听力言语康复效果。方法对行人工耳蜗植入术的2例听神经病患儿进行术前听力学评估，术中、术后听觉诱发电位反应监测及开机后1年的随访，获得其开机后6个月与12个月时的听力言语康复效果，并与人工耳蜗使用时间相近的非听神经病耳蜗植入患儿的康复效果进行对比。结果例1术中神经反应遥测（neural response telemetry，NRT）及电刺激听性脑干诱发反应（electric auditory brainstem response，EABR）可引出波形，但重复性不好，EABR Ⅴ波潜伏期延长。开机12个月时复查，2项电生理检查均引出可重复波形，EABR Ⅴ波潜伏期在正常范围；听力言语康复效果显著提高，开机1年后有意义听觉整合量表得分优于对照组儿童；例2术中NRT未引出有意义波形，EABR可引出波形，但重复性不好；开机12个月复查，2项电生理检查均引出可重复波形，EABR Ⅴ波潜伏期在正常范围；术后听力言语康复效果亦有所提高。结论2例听神经病患者人工耳蜗植入后，术前听觉通路电活动的去同步化均得到一定程度的恢复，听力言语能力也有不同程度提高，说明人工耳蜗植入可以作为听神经病患者实现听力重建，重返主流社会的治疗和康复手段。
Objective To explore the electrophysiological results and rehabilitation outcome of two prelingnally deafened pediatric cochlear implant patients with auditory neuropathy. Methods Preoperative audiological evaluation, intra-postoperative electrically evoked auditory brainstem response （EABR） and neural response telememetry （NRT） record for the two cases were conducted in Beijing Tongren Hospital. A one year follow-up was performed. Data collected before and at 6,12-month intervals after implantation were compared with that from control pediatric cochlear implant patients matched for the same duration of implant use as this two cases. Results The two children implanted had not had any postoperative medical or cochlear implant device complications. Intraoperative EABR and NRT were elicited in case 1 with unrepeatable waveforms. After 12 months of training, Case 1 had shown significant improvements in sound detection, speech perception abilities and communication skills, which was better than the control group, and the electrophysiological results became normal. Case 2 had also benefited from cochlear implantation, even though no recognizable NRT was found until he returned 12 month after the operation. Conclusions The desynchronization of auditory path had been changed after the electrical stimulation ongoing 12 months for children with auditory neuropathy. The two children had not had any complications postoperatively, and each child had shown improved listening and communication skills. Cochlear implantation could help patients with auditory neuropathy to improve their communication skill and go back to the main stream.
出处
《中华耳鼻咽喉头颈外科杂志》
CAS
CSCD
北大核心
2008年第2期100-104,共5页
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
基金
国家自然科学基金资助项目（30572028）
北京市科技新星计划资助项目（9558101300）
北京市自然科学基金资助项目（7032008）
关键词
耳蜗植入术
听觉丧失
感音神经性
耳蜗后疾病
治疗结果
Cochlear implantation
Hearing loss, sensorinerral
Retrocochlear disearses
Treatment outcome
作者简介
通讯作者：韩德民，Email：handm@trhos.com
