摘要
1977年以来,作者行15例肝移植中有12例系肝恶性肿瘤行原位肝移植.无术中及术后即期死亡.存活3个月以上4例,半年以上2例,最长1例近9个月(264天).主要死亡原因为肝功能衰竭、急性排斥、癌肿复发和感染.鉴于对肝癌作肝移植看法仍有分歧,作者提出肝癌新的分期,讨论了移植适应证与手术时机,认为肝移植适宜于肝癌I期b型和Ⅱ期,也有倾向于更早期的.本文分析我国肝病行肝移植结果较差的原因有:癌恶性程度高又过于晚期,经验太少,我国尚未接受脑死亡概念,致供肝质量差和大部分病例未应用环孢素等.
Of the 15 cases of liver transplantation performed inour institute since 1977,12 cases were liver malignan-cy.No intraoperative and immediate postoperativedeath occured.Four cases survived for over 3 months.in whom 2 survived over 6 months,the longest onenear 9 months(264 days).The main casuses of deathwere liver failure,acute rejection.tumor recurrence andinfection.Because controversy still exists in the livertransplantation as an indication for hepatic cancer.anew liver cancer classification.the indication and thetiming to liver transplantation are suggested.It is holdthat the liver transplantation is suitable for the livercancer at stage l.type b and stage I,even more earlystage may be considered.The main reasons for poor re-sult were:PLC was more malignant.too far advanec.less experiece in liver grafting.poor quality of donorliver and CsA was not used in most cases.
作者
夏穗生
刘敦贵
Xia Suisheng;Liu Dungui(Institute of Organ Transplanta-tion.Tongji Medical University,Wuhan 430030)
出处
《中国实用外科杂志》
CSCD
1994年第12期722-724,共3页
Chinese Journal of Practical Surgery
关键词
原位肝移植
肝癌分期
癌
外科手术
肝肿瘤
Liver cancer
Orthotopic liver transplan-tation
Liver cancer classification
