摘要
目的 探讨骨转移癌综合治疗的途径。方法 选择同期住院骨转移癌患者 6 0例 ,随机分为治疗组和对照组 ,每组 30例。两组病例原发灶基本控制后 ,转移病灶采用60 Co或 6mv直线加速器体外局部放疗 (DT 30～ 4 0GY/ 3～ 4周 )。治疗组从放疗开始起 ,使用复方苦参注射液连续至放疗结束。比较两组白细胞计数、碱性磷酸酶值的变化及近期疗效、生存期等指标的差异性。结果 治疗组 90 %的患者至治疗结束时白细胞数均在正常范围 ,碱性磷酸酶下降 >10 0U/L者达 5 3 3% ,远较对照组的 2 3 3%明显 (P <0 0 5 ) ;治疗组和对照组的CR +PR率分别为 96 6 6 % ( 2 9/ 30 )和 6 6 6 6 % ( 2 0 / 30 )。 1年生存率两组无差异 ,但治疗组 4例生存期 >18个月。
Objective To explore the methods of synthetic treatment about metastatic bone cancer.Methods 60 cases of metastatic bone cancer inpatients at the same stage were assigned to treatment group and control group,30 cases each group.After basic control about two groups metastatic bone cancer with synthetic treatemnt,metastatic bone cancer were treated with 60 Co or 6mv straightline speeder at local extracorporeal radiotherapy of DT 30～40GY three to four weeks,and treatment group were simultaneously continuously treated with composite kushen injection 20ml+0.9% NS 250ml ivdrip every day.The differences of two groups cases were compared in respect of count of leukocyte and the changes and early therapeulic effects of ALP and survival duration.Results In the treatment group the count of leukocyte in 90% cases was at normal range and ALP on the decrease of >100U/L was 53.3%,which were significant beyond those in control group.The CR+PR rate of treatment group and control group was respectively 96.66%(29/30) and 66.66%(20/30)(P<0.01).One year survival rate of two groups was no difference,but the survival duration of 4 cases in treatment group was beyond 18 months.Conclusion It is a good method of treatment of matstatic bone cancer and effective control of pains with radiotherapy and composite kushen injection and it has significantly cooperative function,specified clinical significance for the protection of luekocye and the decrease of ALP.
出处
《中国基层医药》
CAS
2004年第7期848-849,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
放疗
复方苦参注射液
联合治疗
骨转移癌
生存期
Metastatic bone cancer
Extracorporeal radiotherapy
Composite kushen injection
Treatment
