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促性腺激素释放激素激动剂联合监测排卵治疗子宫腺肌症合并不孕症的疗效观察 被引量:7

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摘要 目的探讨促性腺激素释放激素激动剂(GnRH-a)联合监测排卵指导受孕治疗子宫腺肌症合并不孕症患者的临床疗效。方法对37例子宫腺肌症合并不孕症患者分为三组进行回顾性分析,使用GnRH-a治疗3个月12例,6个月10例,不同意使用GnRH-a治疗15例为对照组,检测两治疗组治疗前和治疗后、对照组的血清生殖激素[雌二醇(E2)、促卵泡生成激素(FSH)、促黄体生成素(LH)、催乳素(PRL)、黄体酮(P)和睾酮(T)]与CA125水平,超声测定子宫大小和计算半年妊娠率。结果两治疗组治疗后与对照组、治疗前比较,生殖激素、血清CA125、子宫大小均显著降低(P<0.01),半年妊娠率(治疗3个月后达58.33%,治疗6个月后达60.00%)均显著提高(P<0.01),但两治疗组妊娠率相比差异无统计学意义(P>0.05)。结论 GnRH-a对子宫腺肌症患者有一定的治疗作用,用GnRH-a预治疗后再监测排卵指导受孕可以提高受孕率。
出处 《中华临床医师杂志(电子版)》 CAS 2011年第11期3326-3328,共3页 Chinese Journal of Clinicians(Electronic Edition)
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