摘要
目的分析流行性感冒的实验室检查包括血细胞分析、淋巴细胞分型、炎性指标的特点。方法收集2018-12/2019-05月因发热来作者医院感染内科就诊的部队患者147例,其中确诊为甲型流感患者61例、乙型流感患者54例、其他普通上呼吸道感染患者32例的血常规、淋巴细胞分型、血沉(erythrocyte sedimentation rate,ESR)、C-反应蛋白(C-reactive protein,CRP)、白细胞介素6(interleukin 6,IL-6)、降钙素原(procalcitonin,PCT)、铁蛋白(ferritin,Fer)。比较分析3组间数据的差异。结果3组比较,白细胞计数(white blood cell,WBC)、中性粒细胞计数(neutrophils,NEU)、血小板计数(platelet,PLT)、淋巴细胞计数(lymphocyte,LYM)、CD4、T细胞计数、CRP均有统计学差异(P<0.05)。其中甲型流感组、乙型流感组的WBC、NEU、PLT、CD4均低于其他普通上呼吸道感染组,有统计学差异(P<0.05)。乙型流感组LYM低于其他普通上呼吸道感染组,甲型流感组T细胞计数低于其他普通上呼吸道感染组,有统计学差异(P<0.05)。甲型流感组、乙型流感组CRP均低于其他普通上呼吸道感染组,相比有统计学差异(P<0.05)。单核细胞计数(monocyte,MONO)、血红蛋白浓度(hemoglobin,HGB)、B细胞计数、NK细胞计数、Fer、PCT、IL-6、ESR 3组间均无统计学差异(P>0.05)。结论甲型流感、乙型流感与其他普通上呼吸道感染相比在血常规分析、淋巴细胞分型、CRP上有一定差别,而甲型流感、乙型流感间实验室检查结果差异不显著。
Objective To seek the characteristics of influenza laboratory tests,including blood cell analysis,lymphocyte typing,and inflammatory indicators.Methods The date of 147 patients with fever in authors′hospital from December 2018 to May 2019 were collected,including 61 cases of influenza A,54 cases of influenza B,and other common upper respiratory tract infections in 32 patients.Comparative analysis of differences in data including the blood routine,lymphocyte typing,erythrocyte sedimentation rate(ESR),C-reactive protein(CRP),interleukin 6(IL-6),procalcitonin(PCT)and ferritin(Fer)were collected between the three groups.Results There were significant differences in white blood cell(WBC),neutrophils(NEU),platelet(PLT),lymphocyte(LYM),CD4,T cell count and CRP among the three groups(P<0.05).The WBC,NEU,PLT and CD4 counts of influenza A group and influenza B group were all lower than those of other common upper respiratory tract infections group(P<0.05).The LYM of influenza B group was lower than that of other common upper respiratory tract infections group.The total T cell count was significantly different between influenza A group and other common upper respiratory tract infections group.The levels of CRP of influenza A group and influenza B group were lower than those of other common upper respiratory tract infections group(P<0.05).Monocyte(MONO),hemoglobin(HGB),B cell count,NK cell count,Fer,PCT,IL-6 and ESR were not significantly different among three groups.Conclusion Compared with other upper respiratory tract infections,influenza A and influenza B have certain differences in blood routine analysis,lymphocyte typing and CRP,while the results of laboratory tests between influenza A and influenza B are not significantly different.
作者
宋乐
张波
何俊俐
陈吐芬
孔德娜
李军
张艳琼
张秋琼
SONG Le;ZHANG Bo;HE Junli;CHEN Tufen;KONG Dena;LI Jun;ZHANG Yanqiong;ZHANG Qiuqiong(Departmentof Infectious Disease,General Hospital of Central Theater Command,Wuhan Hubei 430070,China)
出处
《华南国防医学杂志》
CAS
2020年第8期577-580,共4页
Military Medical Journal of South China
作者简介
通讯作者:张波,E-mail:xiaobobo@sohu.com