摘要
目的:基于中医传承辅助平台系统(V2.5)软件,挖掘《普济方·消渴门》的用药特点并分析其潜在规律,进一步指导消渴的临床用药。方法:将《普济方·消渴门》的所有处方录入中医传承辅助平台系统,对处方的单味药的频次、常用药对、常用角药,以及药物之间的关联规则等数据进行挖掘。结果:《普济方·消渴门》一共包含方剂674首,涉及药物510味;使用频率最高的药物为麦冬、天花粉、茯苓、人参、黄连;最常见的药对:麦冬+天花粉,人参+茯苓,黄连+天花粉;最常见的角药:麦冬+黄连+天花粉,麦冬+知母+黄连;基于关联规则发现的常见药物组合:黄芪、茯苓→人参(置信度0.8),知母、黄连→麦冬(置信度0.78)。结论:《普济方·消渴门》在治疗消渴病及其并发症的用药以麦冬、天花粉、茯苓、人参为首选药,遵循消渴病阴虚为本、燥热为标的病机,值得临床参考。
Objective:Based on traditional Chinese medicine inheritance auxiliary platform system(V2.5)software,to explore the drug characteristics of"Puji fang·xiaokemen"and analyze its potential law,further guide the clinical drug use of antithirst-related drugs.Methods:All prescriptions of"Puji fang·xiaokemen"were input into the traditional Chinese medicine inheritance assistance system,and the association rules integrated by the software of this system were used to mine the data such as the frequency,common usage,common horn medicines and association rules among drugs.Results:Puji fang·xiaokemen contained 674 prescriptions,involving 510 flavors of drugs.The most frequently used drugs are Dwarf lilyturf,Radix trichosanthis,Poria cocos,Ginseng.The most common drug pairs:Dwarf lilyturf+Radix trichosanthis,Ginseng+Poria cocos,Rhizoma coptidis+Radix trichosanthis;The most common horn medicine:Dwarf lilyturf+Rhizoma coptidis+Radix trichosanthis,Dwarf lilyturf+Rhizoma anemarrhenae+Rhizoma coptidis;Common drug combinations found based on association rules:Radix Astragali,Poria cocos→Ginseng(confidence 0.8),Rhizoma anemarrhenae,Rhizoma coptidis→Radix trichosanthis(confidence 0.78).Conclusion:In the treatment of thirst and its complications Dwarf lilyturf,Radix trichosanthis,Poria cocos and Ginseng are the first choice,It is worthy of clinical reference to follow the principle of Yin deficiency of thirst and heat as the target pathogenesis.
作者
杨倩
郑曙琴
Yang Qian;Zheng Shuqin(Liaoning University of TCM,Shenyang 110032,China;The Affiliated Hospital of Liaoning University of TCM,Shenyang 110032,China)
出处
《亚太传统医药》
2020年第1期159-162,共4页
Asia-Pacific Traditional Medicine
作者简介
杨倩(1993-),女,辽宁中医药大学硕士研究生,研究方向为中医内科学(内分泌方向);通讯作者:郑曙琴(1973-),女,博士,辽宁中医药大学附属医院主任医师,教授,硕士生导师,研究方向为内分泌疾病。E-mail:qxjzsqsina.com
