摘要
目的 探讨经皮骨强化术(PBA)治疗非小细胞肺癌溶骨性胸骨转移瘤的疗效。方法 选取10例经病理证实的非小细胞肺癌溶骨性胸骨转移瘤行PBA的资料,回顾性分析手术治疗方法,采用术前、术后视觉模拟评分(VAS)、KPS评分评估临床疗效。采用SPSS 19.0统计学软件单因素方差分析,对所得数据进行统计学分析,以P<0.05为差异有统计学意义。结果 10例患者均顺利完成手术,术后1周,VAS评分由术前8.60±0.97降至术后2.70±0.67;KPS评分由术前31.00±9.94升至术后77.00±10.59,治疗前后两者差异均有统计学意义(P<0.05)。结论 PBA治疗非小细胞肺癌溶骨性胸骨转移瘤创伤小且安全,可获得良好的止痛效果,有效提高患者的生活质量。
Objective To investigate the efficacy of percutaneous bone augmentation in the treatment of osteolytic sternal me-tastases of non-small cell lung cancer.Methods The data of 10 patients with pathology confirmed osteolytic sterna metastases of non-small cell lung cancer underwent percutaneous bone augmentation treatment were collected.The surgical treatment meth-ods were retrospectively analyzed.The clinical efficacy was evaluated by visual analogue scale(VAS)and karnofsky performance status(KPS)before and after operation.SPSS 19.0 statistical software was used to analyze the data by one-way ANOVA.P<0.05 indicated that the difference was significant.Results All the 10 patients were completed the operation successfully.The VAS score decreased from 8.60±0.97 to 2.70±0.67 after operation,and KPS score decreased from 31.00±9.94 to 77.00±10.59 af-ter operation,and the difference was statistically significant(P<0.05).Conclusion Percutaneous bone augmentation in the treatment of non-small cell lung cancer with osteolytic metastases of sternum can obtain good analgesic effect,improve the behav-ior ability of patients,with less trauma and safety,which can significantly improve the quality of life of patients.
作者
李传海
贺呈祥
刘训伟
吕昌鹏
张梅
LI Chuanhai;HE Chengxiang;LIU Xunwei;LYU Changpeng;ZHANG Mei(Department of Thoracic Surgery,The 960th Hospital of the Joint Logistics Support Unit of the PLA,Jinan 250031,China;Oncology Department of South Campus,The 960th Hospital of the Joint Logistics Support Unit of the PLA,Jinan 250031,China;Department of Thoracic Surgery,Yuncheng County Chengxin Hospital,Heze 274700,China)
出处
《医学影像学杂志》
2024年第8期124-126,共3页
Journal of Medical Imaging
基金
国家自然科学基金项目(编号:81671799)。
关键词
胸骨转移瘤
经皮骨强化术
肺癌
介入性
放射学
Sternal metastases
Percutaneous bone augmentation
Lung cancer
Interventional radiology
作者简介
李传海(1979-),男,毕业于中国医科大学,医学硕士,副主任医师,主要从事胸外科诊疗工作;通信作者:张梅,E-mail:zhangmeiMZ@163.com。
