摘要
乳源外泌体是由乳腺上皮细胞分泌的一种茶杯样纳米级功能性囊泡,其含有多种生物活性物质,具有多种生物学功能,其在靶向载体、药物递送等方面的应用具有天然优势。本文综述了乳源外泌体结构组成、分离鉴定与保存方法、生物学功能及其应用,为乳源外泌体的研究应用提供有价值的参考。
Milk-derived exosomes are teacup like nanoscale functional vesicles secreted by mammary epithelial cells,which contain a variety of bioactive substances and have a variety of biological functions,and have natural advantages in the application of targeting vectors and drug delivery.In this paper,the structural composition and formation process of milk-derived exosomes,methods of isolation,identification and preservation,biological functions and applications of milk exosomes were reviewed,which provided valuable references for the research and application of milk exosomes.
作者
张越
郑好
董霞
陈星
史良玉
余博
周傲
张淑君
ZHANG Yue;ZHENG Hao;DONG Xia;CHEN Xing;SHI Liang-yu;YU Bo;ZHOU Ao;ZHANG Shu-jun(Laboratory of Genetic Breeding,Reproduction and Precision Livestock Farming,School of Animal Science and Nutritional Engineering,Wuhan Polytechnic University,Wuhan 430023;Hubei Key Laboratory of Animal Embryo and Molecular Breeding,Institute of Animal Science and Veterinary Medicine,Hubei Academy of Agricultural Sciences,Wuhan 430064;College of Animal Science and Technology/College of Veterinary Medicine,Huazhong Agricultural University,Wuhan 430070)
出处
《中国奶牛》
2025年第4期16-21,共6页
China Dairy Cattle
基金
湖北省支持种业高质量发展项目(HBZY2023B007)
湖北省高等教育优秀中青年科技创新项目。
关键词
乳源外泌体
分离与鉴定
生物学功能
应用
保存
Milk-derived exosomes
Separation and identification
Biological function
Application
Preservation
作者简介
张越(2002-),女,湖北钟祥人,硕士研究生,主要从事动物抗病育种研究。;通讯作者:周傲,男,湖北钟祥人,副教授,博士,主要从事动物抗病育种研究;通讯作者:张淑君(1966-),女,湖北武穴人,教授,主要从事动物抗病分子遗传育种、牛奶MIR指纹及其生物标记与规模化检测新技术的研究。
